Mac: No Midi I/O PortAudio, No Synthesizer, No Playback

• Apr 8, 2022 - 15:19

Problem: Synthesizer and Mixer are greyed out, playback is greyed out, and external midi doesn't work for entering notes, can't play using internal midi sounds either.

I'm running MacOS 11.6.2 (Big Sur) and MuseScore 3.6.2
From About MuseScore: OS: macOS 10.16, Arch.: x86_64, MuseScore version (64-bit):, revision: 3224f34

MuseScore Preferences -> I/O, port audio is selected, but there is nothing in any of the dropdowns.

I've reviewed this article:

I have done a musescore factory reset, reinstallation, and deleted the .plist files per these other articles (even the advanced reset), as well as safe mode boot and restart.

Starting MuseScore from the command line shows the following:

steve@SMBP16 ~ % /Applications/MuseScore\
dlopen error : dlopen(libjack.0.dylib, 1): image not found
dlopen error : dlopen(/usr/local/lib/libjack.0.dylib, 1): image not found
No device selected. PortAudio detected 3 devices. Will use the default device (index 1).
||PaMacCore (AUHAL)|| Failed to open AUHAL component.||PaMacCore (AUHAL)|| Error on line 1263: err='-50', msg=Unknown Error
||PaMacCore (AUHAL)|| Failed to open AUHAL component.||PaMacCore (AUHAL)|| Error on line 1263: err='-50', msg=Unknown Error
Portaudio open stream 1 failed: Internal PortAudio error
init PortAudio failed
Portaudio close stream failed: Invalid stream pointer
no audio driver found
ZoomBox::setLogicalZoom(): Formatting logical zoom level as 100% (rounded from 1.000000)
Cannot start I/O
sequencer init failed

I have also downloaded the latest PortAudio, compiled and installed:

Still no PortAudio options.

Internal and External Midi instruments works just fine with Logic Pro, and I see external midi data using Midi Monitor.

Any ideas? Thanks!


I'm in the same exact situation. I thought it might have been an issue with some of the Native Instruments things I installed recently. So I wiped my system clean of all NI files and it's still messed up. I'm wondering if you've found any solutions. This just started this morning for me out of the blue. MS worked perfectly yesterday and literally nothing has changed on my computer since the last time I successfully used MS and since it started this morning. Baffling.

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