More measures per system - stretch doesn't work, no of measure/system doesn't work

The vertical Frames you have effectivly are line breaks, also you do have very strange settings for stave- and system distance (0), which make some of these vertical frames neccessary (you could use a spacer instead though, but not for dercreasing distances) and you have set 5 measures per line, Better use line breaks for that and also have a look at the "Break everx X measures" plugin

The easiest way to enlarge a score is to just increase the space value, see http://musescore.org/en/handbook/layout-and-formatting

...would be to compare the settings in this attachment with the ones in your original score:

Under menu item Style / Edit General Style / Page: look at Staff distance and System distance.
Also Lyrics (lower and upper) margin, and Last system fill threshold (spreads out the last system, as you mentioned meas. 104-105 - however, I put 2 more measures on the final line).

Under Style / Edit General Style / System: look at Fix Number of Measures/System. (Musescore does a pretty good job on its own without changing this.)
I got rid of the vertical frames. Also, I needed hardly any line breaks. Like I said, MS does a good job. You can see the effect of line breaks by, for instance, deleting one to see what gets shifted around.

Under Style / Edit Text Style / Measure Number: look at Offset X: This keeps the measure numbers from clashing with the staff.

Also (an excellent tool to use):
"Add More Stretch" and "Add Less Stretch" in the handbook:
http://musescore.org/en/handbook/layout-and-formatting

There is one stubborn vertical frame (on the second line meas. 10-15) which won't go away, but it doesn't print anyway. You can see it by clicking menu item Display / Show Frames.
Lastly, you may want to double check the repeat in measure 101.

Regards...